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What is Anafranil?
Product Description

Common use

Anafranil is a drug used to treat obsessive compulsive disorder (OCD). This is a nervous condition where a person has recurring thoughts or ideas, or does repetitive things because they are anxious.
Clomipramine works on the central nervous system (CNS) and helps to relieve the symptoms of OCD. This medication belongs to a class of so called tricyclic antidepressants. It helps to restore the balance of certain natural substances (serotonin, among others) in the brain.
This medication is also used to treat panic attacks, depression, and ongoing pain.

Dosage and direction

Take the drug only as prescribed because dosage and schedule may vary on your condition and other factors.
It is advised to follow the doctor's instructions carefully and not to take more or less medication than prescribed.
It is advised not to eat grapefruit or drink grapefruit juice ( it influences the level of cyclosporin in your blood ). Also limit alcoholic beverages.
Do not suddenly stop taking this medication as your condition may become worse.
It may take 2 to 3 weeks or longer before you notice the effects of this medication. Inform your doctor about your condition.

Precautions

Before you start taking Clomipramine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.
Inform your doctor or pharmacist if you have certain heart problems (heart failure, slow heartbeat, QT prolongation in the EKG).
You may feel dizzy or drowsy or have temporary blurred vision. Avoid driving, using machinery, or doing any activity that requires alertness.
Aged people may be more sensitive to the side effects of the drug.
During pregnancy this medication should be used only when strongly needed. Consult your doctor about the risks.
This medicine passes into breast milk so it may have undesirable effects on a nursing infant. It is better to stop breast-feeding while using this drug.

Possible side effect

The most common side effects are dizziness, dry mouth, drowsiness, constipation, stomach upset, nausea, vomiting, sweating etc. Anxiety symptoms may temporarily worsen when you first start using Clomipramine.
A serious allergic reaction to this drug is very rare, but seek immediate medical help if it occurs.
Many people using this medicine do not have serious side effects.
In case you notice any side effects not listed above, contact your doctor or pharmacist.

Drug interaction

Tell your doctor or pharmacist of all prescription and nonprescription/herbal products you may use before using this medication.
Avoid taking Clomipramine with:
* MAO inhibitors: Furazolidone, Isocarboxazid, Linezolid, Moclobemide Tranylcypromine, etc.
* anti-arrhythmic medication: Propafenone, Quinidine, etc.
* Selective Serotonin Reuptake Inhibitors (SSRIs): Citalopram, Dapoxetine, Fluoxetine, Fluvoxamine, Paroxetine, etc.
* Antipsychotics (also called neuroleptics): Fluphenazine, etc.
* H2-receptor antagonists: Cimetidine, Ranitidine, Famotidine, Nizatidine, etc.
Nicotine decreases blood levels of this medication. Inform your doctor if you smoke or if you have recently stopped smoking.
Try not to eat grapefruit or drink grapefruit juice while being treated with this medication.
Consult your doctor or pharmacist for more details.

Missed dose

If you have missed your dose, take it as soon as you remember. If you see that it is near the time for the next dose, skip the missed dose and resume your usual dosing schedule. Do not take the dose twice.

Overdose

If you think you have used too much of this medicine seek emergency medical attention right away. The symptoms of overdose usually include chest pain, nausea, irregular heartbeat, and feeling light-headed or fainting.

Storage

Store your medicines at room temperature between 68-77 degrees F (20-25 degrees C) away from light and moisture. Do not store the drugs in the bathroom. Keep all drugs away from children and pets.

Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information on the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.
Uses
Clomipramine is used to treat obsessive compulsive disorder (OCD). It helps decrease persistent/unwanted thoughts (obsessions), and it helps reduce the urge to perform repeated tasks (compulsions such as hand-washing, counting, checking) that interfere with daily living.

This medication belongs to a class of medications called tricyclic antidepressants. It works by restoring the balance of certain natural substances (serotonin, among others) in the brain.

How to use Anafranil
Read the Medication Guide provided by your pharmacist before you start taking clomipramine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.

Take this medication by mouth with or without food as directed by your doctor. To lessen side effects such as stomach upset, clomipramine may be started at a low dose, given in several doses during the day with meals, and slowly increased as your body gets used to it. After you have reached the best dose for you, the total dose can be taken once daily, usually at bedtime to prevent daytime drowsiness or as directed by your doctor. Usually, the daily dose will not be more than 250 milligrams for adults and 200 milligrams for children and teenagers.

Follow your doctor's instructions carefully. Do not take more or less medication or take it more frequently than prescribed. Your condition will not improve any faster and your risk of side effects such as seizures may be increased. Dosage is based on your medical condition and response to therapy.

Avoid eating grapefruit or drinking grapefruit juice while being treated with this medication unless your doctor instructs you otherwise. Grapefruit can increase the amount of certain medications in your bloodstream. Consult your doctor or pharmacist for more details.

Use this medication regularly in order to get the most benefit from it. Continue to take it even if you feel well. To help you remember, use it at the same time(s) each day.

Do not suddenly stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is abruptly stopped. You may experience sweating, dizziness, nausea, vomiting, headache, or irritability if you suddenly stop taking this drug. Your dose may need to be gradually decreased.
Side Effects
See also Warning section.

Dizziness, drowsiness, dry mouth, constipation, stomach upset, nausea, vomiting, changes in appetite/weight, flushing, sweating, tiredness and blurred vision may occur. Anxiety symptoms may temporarily worsen when you first start taking clomipramine. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.

To relieve dry mouth, suck on (sugarless) hard candy or ice chips, chew (sugarless) gum, drink water or use a saliva substitute.

To prevent constipation, maintain a diet adequate in fiber, drink plenty of water, and exercise. If you become constipated while using this drug, consult your pharmacist for help in selecting a laxative (e.g., stimulant-type with stool softener).

Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (e.g., confusion, depression, memory problems), enlarged/painful breasts, unwanted breast milk production, irregular/painful menstrual periods, muscle stiffness, ringing in the ears, sexual problems (e.g., decreased sexual ability, changes in desire), shakiness (tremors), numbness/tingling of the hands/feet, trouble urinating, easy bruising/bleeding, unusual/uncontrolled movements (especially of the tongue/face/lips), severe stomach/abdominal pain, dark urine, yellowing of eyes/skin.

This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take. Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.

Get medical help right away if you have any very serious side effects, including: black stools, chest pain, fainting, slow/fast/irregular heartbeat, seizures, vomit that looks like coffee grounds, eye pain/swelling/redness, widened pupils, vision changes (such as seeing rainbows around lights at night).
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