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Drug Uses

Deltasone is used to reduce inflammation and reduce the symptoms in a variety of conditions like ulcerative colitis, psoriasis and Crohn's disease. It may also be used for other conditions as determined by your doctor.


Use Deltasone exactly as prescribed by your doctor. However, you may take it with a meal to avoid an upset stomach. Do not stop taking it suddenly even if you achieve temporary relief.

Missed Dose

You should try and take your doses on time taking care not to miss any. But if you miss a dose take it as soon as you remember and space out the remaining doses. You may also skip it and continue with your regular dose. But do not take a double dose ever.


Store it at room temperature away from moisture.


Some of the symptoms of an overdose are obesity (especially around the stomach), a round face, swollen hands and feet due to fluid retention and increased blood pressure. Seek medical attention immediately if you suspect an overdose.

More Information

Use it with caution. The drug may cause light-headedness, dizziness, and faintness in some people. Do not consume alcohol along with the drug. Do not drive or handle heavy machinery until you know how to react to the drug. Contact your doctor if your symptoms worsen.


Do NOT use Deltasone (Prednisone) if:

you are allergic to any ingredient in Deltasone (Prednisone)
you have a systemic fungal infection
you are currently taking mifepristone

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Deltasone (Prednisone) . Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
if you are pregnant, planning to become pregnant, or are breast-feeding
if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
if you have allergies to medicines, foods, or other substances
if you are scheduled for a vaccination with a live virus vaccine (eg, smallpox)
if you have an underactive thyroid, liver or kidney problems, diabetes, or ulcerative colitis
if you have heart problems, esophagitis, gastritis, stomach obstruction or perforation, or an ulcer
if you have a history of mental problems, such as depression
if you have a herpes infection in your eye or any other type of infection (bacterial, fungal, or viral); have or recently had tuberculosis (TB) or tested positive for TB, measles, or chickenpox

Some MEDICINES MAY INTERACT with Deltasone (Prednisone) . Tell your health care provider if you are taking any other medicines, especially any of the following:
Barbiturates (eg, phenobarbital), carbamazepine, hydantoins (eg, phenytoin), or rifampin because the effectiveness of Deltasone (Prednisone) may be decreased
Clarithromycin azole antifungals (eg, ketoconazole), steroidal contraceptives (eg, desogestrel), or troleandomycin because side effects, such as weakness, confusion, muscle aches, joint pain, or low blood sugar, may occur
Methotrexate or ritodrine because the actions and side effects of these medicines may be increased
Hydantoins (eg, phenytoin), mifepristone, or live vaccines because the effectiveness of these medicines may be decreased
Anticoagulants (eg, warfarin) or aspirin because the actions and side effects of these medicines may be increased or decreased

Possible Side Effects

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Difficulty sleeping; feeling of a whirling motion; increased appetite; increased sweating; indigestion; mood changes; nervousness.

Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); appetite loss; black, tarry stools; changes in menstrual periods; convulsions; depression; diarrhea; dizziness; exaggerated sense of well-being; fever; general body discomfort; headache; increased pressure in the eye; joint or muscle pain; mood swings; muscle weakness; personality changes; prolonged sore throat, cold, or fever; puffing of the face; severe nausea or vomiting; swelling of feet or legs; unusual weight gain; vomiting material that looks like coffee grounds; weakness; weight loss.

More Information

If you have any questions about Deltasone (Prednisone), please talk with your doctor, pharmacist, or other health care provider.
Deltasone (Prednisone) is to be used only by the patient for whom it is prescribed. Do not share it with other people.
If your symptoms do not improve or if they become worse, check with your doctor.
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